In the year 2032, elite officers Audrey Sterling and Sam Spade are celebrated as local heroes until a desperate scientist, Mr. P, accidentally triggers a viral catastrophe while trying to save his wife. As a glowing orange infection rapidly consumes the city, the officers are forced into a brutal fight for survival through Lucella's sewers and dark alleyways. While the military begins a scorched-earth missile strike to contain the spread, Audrey and Sam navigate the collapsing ruins of the city, eventually discovering that the infection has reached the highest levels of command.